Episode 451 - The Ultimate Getaway! Luffy and His Team's Daring Flight from the Naval Forces

Episode 451
The Great Escape! Luffy and His Crew’s Escape from the Marines
Japanese: 大脱出！ルフィと仲間たち、海軍からの脱出
Dai Dasshutsu! Rufi to Nakama-tachi, Kaigun kara no Dasshutsu

The Straw Hat Pirates arrive at a new island where they discover that it is heavily guarded by a faction of the World Government. The crew learns that this island holds a powerful artifact linked to the world’s history. As they explore further, they realize they must confront the World Government's agents if they want to learn more.